Date | Home Club | Away Club | Video |
| 25/08 | Matlock Town | Whitby Town |  |
| 27/08 | Stamford | Matlock Town | |
| 04/09 | Matlock Town | Worksop Town | |
| 21/09 | Matlock Town | Gateshead | |
20/10 FA Trophy Q1 | Stamford | Matlock Town | |
| 27/10 | Matlock Town | Ossett Town | |
| 17/11 | Lincoln United | Matlock Town | |
| 24/11 | Matlock Town | Guiseley | |
| 1/12 | Whitby Town | Matlock Town | |
| 8/12 | Matlock Town | Kendal Town | |
| 26/12 | Matlock Town | Ilkeston Town | |
| 29/12 | Matlock Town | Leek Town | |
| 19/1/2008 | Matlock Town | Prescot Cables | |
| 16/2 | Matlock Town | Marine | |
| 23/2 | Matlock Town | Eastwood Town | |
| 26/2 | Matlock Town | Witton Albion | |
| 15/3 | Matlock Town | Fleetwood Town | |
| 21/3 | Matlock Town | Buxton | |
| 5/4 | Matlock Town | Frickley Athletic | |
All fixtures are subject to change.
All fixtures are Unibond Premier League Fixtures unless stated
Derbyshire Senior Cup and Unibond Cups will be added when draws are made.
For full fixture list, please click here.